The delivery of agrochemicals is typically achieved by the spraying of fossil‐based polymer dispersions, which might accumulate in the soil and increase microplastic pollution. A potentially sustainable alternative is the use of biodegradable nano‐ or micro‐formulations based on biopolymers, which can be degraded selectively by fungal enzymes to release encapsulated agrochemicals. To date, no hemicellulose nanocarriers for drug delivery in plants have been reported. Xylan is a renewable and abundant feedstock occurring naturally in high amounts in hemicellulose ‐ a major component of the plant cell wall. Herein, xylan from corncobs was used to produce the first fungicide‐loaded xylan‐based nanocarriers by interfacial polyaddition in an inverse miniemulsion using toluene diisocyanate (TDI) as a crosslinking agent. The nanocarriers were redispersed in water and the aqueous dispersions were proven to be active in vitro against several pathogenic fungi, which are responsible for fungal plant diseases in horticulture or agriculture. Besides, empty xylan‐based nanocarriers stimulated the growth of fungal mycelium, which indicated the degradation of xylan in the presence of the fungi, and underlined the degradation as a trigger to release a loaded agrochemical. This first example of crosslinked xylan‐based nanocarriers expands the library of biodegradable and biobased nanocarriers for agrochemical release and might play a crucial role for future formulations in plant protection.

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载有杀菌剂且可生物降解的木聚糖基纳米载体

农用化学品的输送通常是通过喷洒基于化石的聚合物分散体来实现的，这些分散体可能会积聚在土壤中并增加微塑料污染。一种潜在的可持续替代方案是使用基于生物聚合物的可生物降解纳米或微制剂，它们可以被真菌酶选择性降解以释放封装的农用化学品。迄今为止，尚未报道用于植物药物递送的半纤维素纳米载体。木聚糖是一种可再生且丰富的原料，天然存在于半纤维素中——植物细胞壁的主要成分。在此，来自玉米芯的木聚糖用于通过使用甲苯二异氰酸酯 (TDI) 作为交联剂的反相细乳液中的界面加聚来生产第一个负载杀菌剂的木聚糖基纳米载体。纳米载体被重新分散在水中，并且水分散体在体外被证明对几种致病真菌具有活性，这些真菌是园艺或农业中真菌植物病害的原因。此外，空的基于木聚糖的纳米载体刺激真菌菌丝体的生长，这表明木聚糖在真菌存在下降解，并强调降解是释放负载农用化学品的触发因素。这个基于交联木聚糖的纳米载体的第一个例子扩展了用于农用化学品释放的可生物降解和生物基纳米载体的库，并可能对未来的植物保护配方发挥关键作用。此外，空的基于木聚糖的纳米载体刺激真菌菌丝体的生长，这表明木聚糖在真菌存在下降解，并强调降解是释放负载农用化学品的触发因素。这个基于交联木聚糖的纳米载体的第一个例子扩展了用于农用化学品释放的可生物降解和生物基纳米载体的库，并可能对未来的植物保护配方发挥关键作用。此外，空的基于木聚糖的纳米载体刺激真菌菌丝体的生长，这表明木聚糖在真菌存在下降解，并强调降解是释放负载农用化学品的触发因素。这个基于交联木聚糖的纳米载体的第一个例子扩展了用于农用化学品释放的可生物降解和生物基纳米载体的库，并可能对未来的植物保护配方发挥关键作用。