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Preparation of novel symmetrical bistetrazole‐carbazole derivatives through a one‐pot Ugi‐azide reaction
Journal of Heterocyclic Chemistry ( IF 2.4 ) Pub Date : 2020-12-12 , DOI: 10.1002/jhet.4206
Shahnaz Rahimi 1 , Mehdi Ghandi 1
Affiliation  

A series of new symmetrical tetrazole‐based carbazole derivatives starting from the initially generated 3,6‐diformyl‐N‐alkylcarbazoles were successfully synthesized through a one‐pot Ugi‐azide reaction in moderate to high yields. Simplicity, easily accessible chemicals, mild reaction conditions, and fast separation of the products with the formation of bistetrazole‐based carbazole derivatives in one step are some advantages of this method. The structure of the products was characterized and confirmed by using spectroscopic techniques such as 1H NMR, 13C NMR, FT‐IR, and MS spectroscopy.

中文翻译:

通过一锅Ugi-叠氮化物反应制备新型对称的双苯乙烯-咔唑-咔唑衍生物

通过一锅Ugi-叠氮化物反应,以中等到高收率成功合成了一系列新的对称的基于四唑的咔唑衍生物,这些衍生物是从最初生成的3,6-二甲酰基-N-烷基咔唑开始的。这种方法的优点是简单,易于获得的化学药品,温和的反应条件以及快速分离产物并在一个步骤中形成基于联苯二唑的咔唑衍生物。使用1 H NMR,13 C NMR,FT-IR和MS光谱等光谱技术对产品的结构进行表征和确认。
更新日期:2020-12-12
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