The goal of this paper is to present a dedicated high-performance computing (HPC) infrastructure which is used in the development of a so-called reduced-order model (ROM) for simulating the outcomes of interventional procedures which are contemplated in the treatment of valvular heart conditions. Following a brief introduction to the problem, the paper presents the design of a model execution environment, in which representative cases can be simulated and the parameters of the ROM fine-tuned to enable subsequent deployment of a decision support system without further need for HPC. The presentation of the system is followed by information concerning its use in processing specific patient cases in the context of the EurValve international collaboration.

本文的目的是提出一种专用的高性能计算 (HPC) 基础设施，该基础设施用于开发所谓的降阶模型 (ROM)，以模拟在治疗中考虑的介入程序的结果。瓣膜性心脏病。在对该问题进行简要介绍之后，本文介绍了模型执行环境的设计，其中可以模拟代表性案例并微调 ROM 的参数，以便后续部署决策支持系统而无需进一步的 HPC。该系统的介绍之后是有关其在 EurValve 国际合作背景下处理特定患者病例的信息。