Microchimerism is the presence of a small quantity of cells or DNA from a genetically distinct individual. This phenomenon occurs with bidirectional maternal‐fetal exchange during pregnancy. Microchimerism can persist for decades after delivery and have long‐term health implications. However, little is known about why microchimerism is detectable at varying levels in different individuals. We examine the variability and the following potential determinants of maternal‐origin microchimerism (MMc) in young women in the Philippines: gestational duration (in utero exposure to MMc), history of being breastfed (postpartum exposure to MMc), maternal telomere length (maternal cells' ability to replicate and persist), and participant's pregnancies in young adulthood (effect of adding fetal‐origin microchimerism to preexisting MMc).

中文翻译：

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菲律宾年轻女性母源性微嵌合体的预测因子

微嵌合现象是指存在来自基因不同个体的少量细胞或 DNA。这种现象发生在怀孕期间的双向母胎交换中。微嵌合现象可以在分娩后持续存在数十年，并对健康产生长期影响。然而，很少有人知道为什么微嵌合现象在不同个体的不同水平上是可检测的。我们检查了菲律宾年轻女性母源性微嵌合体 (MMc) 的变异性和以下潜在决定因素：妊娠期（子宫内暴露于 MMc）、母乳喂养史（产后暴露于 MMc）、母体端粒长度（母体细胞复制和持续存在的能力），以及参与者在成年早期的怀孕情况（将胎儿来源的微嵌合体添加到预先存在的 MMc 中的效果）。