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The Peculiar Features of Cognitive Processes in Rats Exposed to a Hypomagnetic Field Using Moderate Magnetic Shielding
Biophysics Pub Date : 2020-09-01 , DOI: 10.1134/s0006350920050097
D. R. Khusainov , I. I. Korenyuk , V. I. Shakhmatova , K. N. Tumanyants , N. S. Tribrat , E. D. Khorolskaya , A. V. Chajka , I. A. Borzova

This paper is focused on the dynamics of the formation of conditioned responses in rats that experienced 14-day moderate magnetic shielding and were placed into a shelter setup when conducting the Barnes maze task. It was found that the acquisition rate of the conditioned active avoidance response was faster in rats under magnetic shielding conditions than that in the control animals. A direct accelerating effect of a moderate geomagnetic environment on the acquisition of the conditioned active avoidance response is thought to be extremely unlikely and the observed effect appears to be due to well-known biorhythm changes in pain sensitivity in hypomagnetic conditions associated with the development of hyperalgesia during the first week, which is an additional motivation for the formation of the conditioned active avoidance response in the Shelter setup. A two-phase change in pain sensitivity of male rats for a 14-day period was shown in the electrostimulation setup: hyperalgesia occurred during the first week and hypoalgesia was induced during the second week. The Barnes maze task did not reveal any differences between groups of control animals and experimental animals in recorded behavioral indices in hypomagnetic conditions within a 14-day period. Therefore, the accelerated formation of conditioned active avoidance response in rats under hypomagnetic conditions is most likely due to a significant increase in pain sensitivity during the first week of the experiment.

中文翻译:

使用中等磁屏蔽暴露于弱磁场的大鼠认知过程的特殊特征

本文重点研究经历 14 天中等磁屏蔽并在进行巴恩斯迷宫任务时被置于庇护所设置的大鼠中条件反应形成的动力学。结果表明,磁屏蔽条件下大鼠条件性主动回避反应的获得率高于对照组。中等地磁环境对条件性主动回避反应的获得的直接加速效应被认为是极不可能的,观察到的效应似乎是由于与痛觉过敏的发展相关的低磁条件下疼痛敏感性的众所周知的生物节律变化在第一周,这是在庇护所设置中形成条件主动回避反应的额外动机。在电刺激设置中显示了雄性大鼠在 14 天期间的疼痛敏感性的两阶段变化:第一周发生痛觉过敏,第二周诱发痛觉减退。Barnes 迷宫任务在 14 天内在低磁条件下记录的行为指数中没有显示对照动物组和实验动物组之间的任何差异。因此,在弱磁条件下,大鼠条件性主动回避反应的加速形成很可能是由于实验第一周疼痛敏感性的显着增加。在电刺激设置中显示了雄性大鼠在 14 天期间的疼痛敏感性的两阶段变化:第一周发生痛觉过敏,第二周诱发痛觉减退。Barnes 迷宫任务在 14 天内在低磁条件下记录的行为指数中没有显示对照动物组和实验动物组之间的任何差异。因此,在弱磁条件下,大鼠条件性主动回避反应的加速形成很可能是由于实验第一周疼痛敏感性的显着增加。在电刺激设置中显示了雄性大鼠在 14 天期间的疼痛敏感性的两阶段变化:第一周发生痛觉过敏,第二周诱发痛觉减退。Barnes 迷宫任务在 14 天内在低磁条件下记录的行为指数中没有显示对照动物组和实验动物组之间的任何差异。因此,在弱磁条件下,大鼠条件性主动回避反应的加速形成很可能是由于实验第一周疼痛敏感性的显着增加。Barnes 迷宫任务在 14 天内在低磁条件下记录的行为指数中没有显示对照动物组和实验动物组之间的任何差异。因此,在弱磁条件下,大鼠条件性主动回避反应的加速形成很可能是由于实验第一周疼痛敏感性的显着增加。Barnes 迷宫任务在 14 天内在低磁条件下记录的行为指数中没有显示对照动物组和实验动物组之间的任何差异。因此,在弱磁条件下,大鼠条件性主动回避反应的加速形成很可能是由于实验第一周疼痛敏感性的显着增加。
更新日期:2020-09-01
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