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Research on porous titanium implants and its animal experiments
Rapid Prototyping Journal ( IF 3.9 ) Pub Date : 2020-12-09 , DOI: 10.1108/rpj-06-2019-0170
Chunyan Yao , Dongdong Chen , Zhongli Zheng , Qiangsheng Wang , Kaijie Fu

Purpose

The purpose of this study is to obtain an effective implant with porous structures on its surface, named porous-surfaced implant, which helps to improve the overall stability of the implant and promote the combination of implant and alveolar bone.

Design/methodology/approach

Porous-surfaced implants with a porosity of 16%, 21%and 32% were designed and the effect of porosity on the strength of the implant was analyzed by ABAQUS software. Porous-surfaced implants with different porosity were printed by selective laser melting and the surface morphology was observed. Animal experiments of implants with porous structures and coating were carried out in healthy beagle dogs. The experimental group was treated with hydroxyapatite coating and the control group was not treated. Bone volume (BV) and total volume (TV) of the implant surface of the experimental group and control group were calculated by Skyscan CTvol software.

Findings

With the increase of porosity of porous-surfaced implants, the neck stress of the porous-surfaced implants increased and their strength decreased. In addition, in animal vivo experiments, the ratio value of BV to TV of the porous-surfaced implants was between 55.38% and 79.86%, which was the largest when the porosity of porous-surfaced implants was 16%. The internal and surrounding bone formation content of porous-surfaced implants with hydroxyapatite coating was higher than porous-surfaced implants without coating.

Originality/value

The results of this study show that the pores on the surface of implants can be filled with the new bone and porous-surfaced implants with 16% porosity provide better space for the growth of new bone. The porous structures with hydroxyapatite coating are beneficial to the growth of new bone around implants. The results of this study are helpful to improve the overall stability of implants and to promote the combination of implant and alveolar bone.



中文翻译:

多孔钛植入物的研究及其动物实验

目的

这项研究的目的是获得一种在表面上具有多孔结构的有效植入物,称为多孔表面植入物,这有助于改善植入物的整体稳定性并促进植入物与牙槽骨的结合。

设计/方法/方法

设计了孔隙率分别为16%,21%和32%的多孔表面植入物,并通过ABAQUS软件分析了孔隙度对植入物强度的影响。通过选择性激光熔融印刷具有不同孔隙率的多孔表面植入物,并观察其表面形态。在健康的比格犬中进行了具有多孔结构和涂层的植入物的动物实验。实验组用羟基磷灰石涂层治疗,对照组不治疗。用Skyscan CTvol软件计算实验组和对照组种植体表面的骨体积(BV)和总体积(TV)。

发现

随着多孔表面植入物孔隙率的增加,多孔表面植入物的颈应力增加,强度降低。另外,在动物体内实验中,多孔表面植入物的BV与TV的比率值在55.38%至79.86%之间,这在多孔表面植入物的孔隙率为16%时最大。具有羟基磷灰石涂层的多孔表面植入物的内部和周围骨形成含量高于没有涂层的多孔表面植入物。

创意/价值

这项研究的结果表明,植入物表面的孔可以被新骨填充,孔隙率为16%的多孔表面植入物为新骨的生长提供了更好的空间。羟基磷灰石涂层的多孔结构有利于植入物周围新骨的生长。这项研究的结果有助于改善植入物的整体稳定性,并促进植入物与牙槽骨的结合。

更新日期:2021-01-08
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