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Acute lung injury in mechanically ventilated patients with epidermal necrolysis: an exposed-unexposed retrospective cohort study
Burns & Trauma ( IF 5.3 ) Pub Date : 2020-12-08 , DOI: 10.1093/burnst/tkaa041
S Lalevée 1, 2 , J Catano 3 , S Ingen-Housz-Oro 1, 4, 5 , M Surenaud 2 , J Tran Van Nhieu 6 , F Schlemmer 2, 7 , I Bendib 2, 3, 8 , A Mekontso-Dessap 2, 8 , S Hue 2, 5, 9 , N de Prost 2, 3, 5, 8
Affiliation  

Highlights
  • At the acute phase of epidermal necrolysis, patients requiring mechanical ventilation had more alveolar macrophages and higher alveolar concentrations of IL-13 than age- and sex-matched patients with the acute respiratory distress syndrome
  • Patients with epidermal necrolysis also showed longer duration of mechanical ventilation and more frequent ventilator-acquired pneumonia episodes


中文翻译:

机械通气表皮坏死患者的急性肺损伤:一项暴露-未暴露的回顾性队列研究

强调
  • 在表皮坏死的急性期,与年龄和性别相匹配的急性呼吸窘迫综合征患者相比,需要机械通气的患者的肺泡巨噬细胞数量和肺泡中IL-13浓度更高
  • 表皮坏死患者的机械通气时间也更长,呼吸机获得性肺炎发作频率更高
更新日期:2020-12-09
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