Abstract

This meta-analysis was performed to investigate whether calcium supplements and dairy products change obesity indices including fat mass. Original articles published in English between July 2009 and August 2019 were identified. Ten and 14 randomised controlled trials (RCTs) with ≥ 12 weeks interventions of calcium supplements and dairy products among overweight or obese adults aged ≥18 were critically reviewed. Mean difference (MD) or standardised mean difference (SMD) with 95% confidence interval (CI) were obtained using a random effect meta-analysis. Dairy products significantly changed fat mass (SMD, 95% CI; −0.40 [−0.77, −0.02]) and BMI (MD, 95% CI: −0.46 kg/m2 [−0.67, −0.26]), and calcium supplements also showed changes in fat mass (SMD, 95% CI; −0.15[−0.28, −0.02]). However, in the analysis of RCTs with low risk of bias scores, the significant changes remained only in the dairy-products intervention. Our findings suggest that dairy products without distinction of fat percentage may help reduce fat mass and BMI, but calcium supplements may not.

摘要

进行这项荟萃分析，以调查钙补充剂和乳制品是否会改变包括脂肪量在内的肥胖指数。确定了2009年7月至2019年8月之间以英文发表的原始文章。对10例和14例18岁以上超重或肥胖成年人进行钙补充剂和乳制品干预≥12周的随机对照试验（RCT）进行了严格审查。使用随机效应荟萃分析获得具有95％置信区间（CI）的均值差（MD）或标准化均值差（SMD）。乳制品显着改变了脂肪质量（SMD，95％CI； -0.40 [-0.77，-0.02]）和BMI（MD，95％CI：-0.46 kg / m2 [-0.67，-0.26]），还补充了钙表现出脂肪量的变化（SMD，95％CI； -0.15 [-0.28，-0.02]）。但是，在偏倚得分风险较低的RCT中，重大变化仅保留在乳制品干预中。我们的研究结果表明，不区分脂肪百分比的乳制品可以帮助减少脂肪量和BMI，但钙补充剂则不能。