Aims: This study was undertaken to examine how a layperson is likely to interpret genetic information delivered in a clinical setting. Methods: A novel survey was designed to engage the reader in a simulated discussion of heritability as it might relate to human disease. The survey took approximately 5 min to administer. 307 individuals of different backgrounds completed the survey in the outpatient waiting room on their cell phone. Results: Overall, basic knowledge of inheritance and the concepts of heredity scored very well in the study cohort. Both knowledge and interpretation questions were answered correctly more often than not. There was generally no association between the scores on survey and gender or age. Conclusions: People recognize the basic concepts of heritability but struggle with real-life interpretations and more nuanced concepts of heredity.

中文翻译：

---

通过使用参与的现实生活调查评估对遗传和遗传变异的理解

目的：本研究旨在检查外行人可能如何解释临床环境中提供的遗传信息。方法：设计了一项新颖的调查，让读者参与对遗传性的模拟讨论，因为它可能与人类疾病有关。调查耗时约 5 分钟。307名不同背景的人在门诊候诊室用手机完成了调查。结果：总体而言，遗传的基本知识和遗传概念在研究队列中得分很高。知识和解释问题的回答往往正确。调查分数与性别或年龄之间通常没有关联。结论：