Uric acid is the end product of purine metabolism in humans. High uric acid levels form sodium urate crystals that trigger biological processes, which lead to the development of several diseases, including diabetes, hyperuricemia, gout, inflammatory disease, kidney disease, cardiovascular disease and hypertension. Catechins have been suggested to be beneficial for the regulation of uric acid metabolic disorders due to their powerful antioxidant and anti-inflammatory properties. To identify an effective and safe natural substance that can decrease levels of serum uric acid to improve uric acid metabolism disorders. A search was performed on PubMed, Web of Science and Google Scholar to identify comprehensive studies that presented summarized data on the use of catechins in lowering uric acid levels in diseases. This review details the role of catechins in inhibiting the activity of xanthine oxidase to decrease uric acid overproduction in the liver and in regulating expressions of uric acid transporters, URAT1, OAT1, OAT3, ABCG2 and GLUT9, to balance levels of uric acid secretion and reabsorption through the kidney and intestine. Additionally, Catechins were also found to prevent monosodium urate-induced inflammatory reactions. In vivo, catechins can be used to decrease high uric acid levels that result from hyperuricemia and related diseases. Catechins can be used to maintain the balance of uric acid metabolism.

尿酸是人类嘌呤代谢的最终产物。高尿酸水平会形成尿酸钠晶体，从而触发生物过程，从而导致多种疾病的发展，包括糖尿病，高尿酸血症，痛风，炎性疾病，肾脏疾病，心血管疾病和高血压。儿茶素由于其强大的抗氧化剂和抗炎特性，已被认为对调节尿酸代谢紊乱有益。鉴定可以降低血清尿酸水平以改善尿酸代谢紊乱的有效且安全的天然物质。在PubMed，Web of Science和Google Scholar中进行了搜索，以鉴定综合研究，这些综合研究提供了有关儿茶素在降低疾病中尿酸水平方面的用途的汇总数据。这篇综述详细介绍了儿茶素在抑制黄嘌呤氧化酶的活性以减少肝脏中尿酸过量产生以及调节尿酸转运蛋白URAT1，OAT1，OAT3，ABCG2和GLUT9的表达以平衡尿酸分泌和再吸收水平方面的作用。通过肾脏和肠子。此外，还发现儿茶素能预防尿酸钠对尿酸的诱导反应。在体内，儿茶素可用于降低由高尿酸血症和相关疾病引起的高尿酸水平。儿茶素可用于维持尿酸代谢的平衡。平衡尿酸通过肾脏和肠道的分泌和再吸收水平。此外，还发现儿茶素能预防尿酸钠对尿酸的诱导反应。在体内，儿茶素可用于降低由高尿酸血症和相关疾病引起的高尿酸水平。儿茶素可用于维持尿酸代谢的平衡。平衡尿酸通过肾脏和肠道的分泌和再吸收水平。此外，还发现儿茶素能预防尿酸钠对尿酸的诱导反应。在体内，儿茶素可用于降低由高尿酸血症和相关疾病引起的高尿酸水平。儿茶素可用于维持尿酸代谢的平衡。