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Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data
GigaScience ( IF 9.2 ) Pub Date : 2020-12-07 , DOI: 10.1093/gigascience/giaa134
Sanjit Singh Batra 1 , Michal Levy-Sakin 2 , Jacqueline Robinson 3 , Joseph Guillory 4 , Steffen Durinck 4, 5 , Tauras P Vilgalys 6 , Pui-Yan Kwok 2, 3 , Laura A Cox 7, 8 , Somasekar Seshagiri 4 , Yun S Song 1, 9, 10 , Jeffrey D Wall 3
Affiliation  

Baboons are a widely used nonhuman primate model for biomedical, evolutionary, and basic genetics research. Despite this importance, the genomic resources for baboons are limited. In particular, the current baboon reference genome Panu_3.0 is a highly fragmented, reference-guided (i.e., not fully de novo) assembly, and its poor quality inhibits our ability to conduct downstream genomic analyses.

中文翻译:

使用长读长和 Hi-C 数据准确组装橄榄狒狒 (Papio anubis) 基因组

狒狒是一种广泛用于生物医学、进化和基础遗传学研究的非人类灵长类动物模型。尽管如此重要,狒狒的基因组资源仍然有限。特别是,当前的狒狒参考基因组Panu_3.0是高度碎片化的、参考引导(即不是完全从头)组装的,其质量差抑制了我们进行下游基因组分析的能力。
更新日期:2020-12-07
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