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The Anti‐G0 Manifesto: Should a problematic construct (G0) with no biological reality be removed from the cell cycle? Yes!
BioEssays ( IF 4 ) Pub Date : 2020-12-06 , DOI: 10.1002/bies.202000270
Stephen Cooper 1, 2
Affiliation  

It is widely accepted that there exists a “resting” or “quiescent” state where a growing cell leaves the cell cycle to enter what is often called the “G0‐phase.” I propose that there is no biological reality to the “G0‐phase.” The experimental basis for proposing a G0‐phase is re‐examined and re‐analyzed here showing that the G0‐phase is an anthropomorphic construct with no biological reality.

中文翻译:

抗 G0 宣言:是否应该从细胞周期中去除没有生物学现实的有问题的构建体 (G0)?是的!

人们普遍认为,存在一种“静止”或“静止”状态,即生长中的细胞离开细胞周期进入通常称为“G0 期”的阶段。我认为“G0 阶段”没有生物学现实。这里重新审视和重新分析了提出 G0 阶段的实验基础,表明 G0 阶段是一个没有生物学现实的拟人化结构。
更新日期:2020-12-06
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