Abstract Mixed ligand copper (II) and cobalt (II) complexes viz; [Cu(6-pic)2(succinimie)2] 1; [Cu(6-pic)2(phthalimide)2] 2; [Co(6-pic)2(succinimide)2] 3; [Co(6-pic)2(phthalimide)2] 4 have been synthesized with picolinic acid (6-picolinic acid) and imides (imides = succinimide and phthalimide), used as primary and secondary ligands respectively. All these mixed-ligand complexes (1-4) were characterized by elemental analysis (C H N), molar conductance, room temperature magnetic susceptibility, FT-IR, and UV-Visible spectroscopy. The electrochemical study of all these complexes were performed in aqueous medium, containing 0.2 M NaClO4 as supporting electrolyte at glassy carbon working electrode (GCE) vs Ag/AgCl reference electrode by using cyclic voltammetric (CV). The complexes 1, 2 and 3, 4 were exhibited Cu2+/+ and Co3+/2+ / Co+/2+ diffusion controlled quasi-reversible single electron transfer redox couples. The cobalt (II) complexes 3 and 4 are biologically (in vitro) more active compare to copper (II) complexes 1 and 2 against microorganisms with antibacterial and antifungal drugs.

中文翻译：

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吡啶甲酸和酰亚胺的混合配体铜 (II) 和钴 (II) 配合物的合成、表征、生物（体外）活性和电化学研究

摘要 混合配体铜 (II) 和钴 (II) 配合物即；[Cu(6-pic)2(succinimie)2] 1; [Cu(6-pic)2(邻苯二甲酰亚胺)2]2；[Co(6-pic)2(琥珀酰亚胺)2]3；[Co(6-pic)2(phthalimide)2] 4 已经用吡啶甲酸（6-吡啶甲酸）和酰亚胺（酰亚胺=琥珀酰亚胺和邻苯二甲酰亚胺）合成，分别用作主要和次要配体。所有这些混合配体配合物 (1-4) 都通过元素分析 (CHN)、摩尔电导、室温磁化率、FT-IR 和紫外-可见光谱进行表征。所有这些复合物的电化学研究都是在含有 0.2 M NaClO4 作为玻璃碳工作电极 (GCE) 与 Ag/AgCl 参比电极的支持电解质的水性介质中进行的，使用循环伏安法 (CV)。复合物 1、2 和 3，4个表现出Cu2+/+和Co3+/2+/Co+/2+扩散控制的准可逆单电子转移氧化还原对。与铜 (II) 配合物 1 和 2 相比，钴 (II) 配合物 3 和 4 在生物学上（体外）对具有抗菌和抗真菌药物的微生物具有更高的活性。