Background Klebsiella pneumoniae (K. pneumoniae) strains have been divided into two major categories: classical K. pneumonia, which are frequently multidrug-resistant and cause hospital-acquired infections in patients with impaired defenses, and hypervirulent K. pneumoniae, which cause severe disseminated community-acquired infections in immunologically normal hosts. Both types of infections may lead to bacteremia and are associated with significant morbidity and mortality. The relative burden of these two types of K. pneumoniae among bloodstream isolates within the United States is not well understood.

中文翻译：

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美国学术医疗中心血液分离株中耐多药或高毒性肺炎克雷伯菌的基因组监测

背景 肺炎克雷伯菌（K.pneumoniae）菌株已分为两大类：经典的肺炎克雷伯菌，通常具有多重耐药性并导致防御受损患者的医院获得性感染，以及高毒力的肺炎克雷伯菌，可导致严重的播散性感染。免疫正常宿主的社区获得性感染。这两种类型的感染都可能导致菌血症，并与显着的发病率和死亡率相关。这两种类型的肺炎克雷伯菌在美国血液分离物中的相对负担尚不清楚。