This pilot study's goal was to investigate the impacts of static magnetic fields (SMF) on finger skin blood perfusion (SBP) when exposing the ulnar artery and ulnar and medial nerves to a rare earth concentric magnet for 30 minutes. Control SBP was measured in 4th fingers of adults (n = 12, age 26.0 ± 1.4 years) for 15 minutes using laser-Doppler. Then, active-magnets were placed over one arm's ulnar and median nerves at the wrist and sham-magnets placed at corresponding sites on the other arm. Devices were randomly assigned and placed by an investigator "blinded" to device type. The maximum SMF perpendicular to skin was 0.28 T measured 2 mm from magnet surface. The tangential field at this distance was 0.20 T. SBP was analyzed and tested for differential effects attributable to magnets compared to shams in each of the 5-minute intervals over the full 45-minute experiment. Results showed no statistically significant difference between SBP measured on the magnet-treated side compared to the sham side. Magnet and sham side SBP values (mean ± SEM, arbitrary units) prior to device placement were 0.568 ± 0.128 vs. 0.644 ± 0.115, p = .859 and during device placement were 0.627 ± 0.135 vs. 0.645 ± 0.117, p = .857. In conclusion, these findings have failed to uncover any significant effects of the static magnetic field on skin blood perfusion in the young healthy adult population evaluated. Its potential for altering SBP in more mature persons or those with underlying conditions affecting blood flow has not been evaluated but represents the next target of research inquiry. ClinicalTrials.gov registration number is NCT04539704.

中文翻译：

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尺神经和正中神经暴露于稀土磁铁静磁场期间的手指皮肤血液灌注：一项随机试验研究

该试点研究的目标是研究将尺动脉、尺神经和内侧神经暴露于稀土同心磁体 30 分钟时静磁场 (SMF) 对手指皮肤血液灌注 (SBP) 的影响。使用激光多普勒在成人（n = 12，年龄 26.0 ± 1.4 岁）的第 4 指中测量对照 SBP 15 分钟。然后，将有源磁铁放置在一只手臂手腕的尺神经和正中神经上，并将假磁铁放置在另一只手臂的相应部位。设备由对设备类型“不知情”的研究人员随机分配和放置。垂直于皮肤的最大 SMF 为 0.28 T，在距磁体表面 2 毫米处测得。该距离处的切向场为 0.20 T。在整个 45 分钟的实验中，在每 5 分钟的间隔中，对 SBP 进行了分析和测试，以了解磁铁与假手术的不同效应。结果显示，与假手术侧相比，在磁体处理侧测量的 SBP 之间没有统计学上的显着差异。设备放置前的磁铁和假侧 SBP 值（平均值±SEM，任意单位）为 0.568 ± 0.128 与 0.644 ± 0.115，p = .859，并且在设备放置期间为 0.627 ± 0.135 与 0.645 ± 0.185，p = 7 . 总之，这些发现未能揭示静磁场对所评估的年轻健康成年人群的皮肤血液灌注有任何显着影响。它改变更成熟的人或具有影响血流的潜在条件的人的 SBP 的潜力尚未得到评估，但代表了研究调查的下一个目标。ClinicalTrials.gov 注册号是 NCT04539704。