Background:

Following the implementation of the European Union Tobacco Product Directive (EU TPD) regulations on e-cigarette products in 2016, we assessed the current profile of e-cigarette liquid exposure incidents and their associated health outcomes.

Methods:

De-identified data were received from poison centers in eight EU Member States (Sweden, the Netherlands, Italy, Hungary Austria, Finland, Spain and Croatia) reporting on e-cigarette liquid exposure incidents between August 2018 to December 2019. Descriptive analysis was conducted to present incident characteristics and health outcomes. Chi-square tests and multivariable logistic regression analysis were used to test associations.

Results:

Of the 223 e-liquid exposure incidents recorded by poison centers in multiple EU MS, 64.7% of the cases were unintentional exposures, ranging from 48.4% among adults aged ≥19 years to 100.0% among children aged 0–5 years (p < 0.05). The most frequent route of exposure was ingestion (73.5%) while55.2% experienced any clinical symptoms, including nausea (16.6%), vomiting (11.1%), and dizziness (9.0%). 57.8% of the cases were treated at the residence or on-site.

Conclusion:

Further monitoring is warranted, using uniform reporting requirements, to ensure the continued compliance to the EU TPD and assess its long-term impact on related incident characteristics.

中文翻译：

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2018-2019 年欧洲偶然接触电子烟液体的概况

背景：

继 2016 年对电子烟产品实施欧盟烟草产品指令 (EU TPD) 法规后，我们评估了电子烟液体暴露事件的当前概况及其相关的健康结果。

方法：

从八个欧盟成员国（瑞典、荷兰、意大利、匈牙利、奥地利、芬兰、西班牙和克罗地亚）的毒物中心收到了去标识化数据，报告了 2018 年 8 月至 2019 年 12 月期间的电子烟液体暴露事件。进行了描述性分析呈现事件特征和健康结果。卡方检验和多变量逻辑回归分析用于检验关联。

结果：

在多个欧盟 MS 毒物中心记录的 223 起电子烟油暴露事件中，64.7% 的案例是无意暴露，范围从 19 岁以上成人的 48.4% 到 0-5 岁儿童的 100.0%（p < 0.05 ）。最常见的接触途径是摄入 (73.5%)，而 55.2% 出现任何临床症状，包括恶心 (16.6%)、呕吐 (11.1%) 和头晕 (9.0%)。57.8%的病例在住所或现场接受治疗。

结论：

有必要使用统一的报告要求进行进一步监控，以确保持续遵守欧盟 TPD 并评估其对相关事件特征的长期影响。