Locoregional therapies (lrts) play an important role in the treatment of hepatocellular carcinoma (hcc), with the aim of increasing overall survival while preserving liver function. Various forms of lrt are available, and choosing the best one depends on technical aspects, liver morphology, tumour biology, and the patient's symptoms. The purpose of the present review article is to provide an overview of the current evidence relating to the use of percutaneous ablation, transarterial chemoembolization, and transarterial radioembolization for the curative or palliative treatment of hcc. Special situations are also reviewed, including the combined use of systemic therapy and lrt, indications and techniques for bridging to transplant and downstaging, and the use of lrt to treat patients with hcc and macrovascular invasion.

中文翻译：

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当前肝细胞癌的局部治疗和治疗策略

局部区域疗法 (lrts) 在肝细胞癌 (hcc) 的治疗中发挥着重要作用，其目的是在保持肝功能的同时提高总体存活率。有多种形式的 lrt，选择最好的一种取决于技术方面、肝脏形态、肿瘤生物学和患者的症状。本综述文章的目的是概述有关使用经皮消融、经动脉化学栓塞和经动脉放射栓塞治疗 hcc 的当前证据。还回顾了特殊情况，包括全身治疗和 lrt 的联合使用、过渡到移植和降期的适应症和技术，以及 lrt 用于治疗 hcc 和大血管侵犯的患者。