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Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord.
International Neurourology Journal ( IF 2.3 ) Pub Date : 2020-11-23 , DOI: 10.5213/inj.2040448.224
Young Sam Cho , Su Jin Kim , Khae Hawn Kim

Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitors have been proposed as a promising option for inducing neural regeneration. Therefore, we investigated the effects of a tissue gene nerve (TGN), PTEN inhibitor, on voiding function, motor function, and the expression of growth factors after SCI.

中文翻译:

脊髓损伤后PTEN抑制剂对脊髓再生后观察到的排空效率和运动功能恢复的评估。

与脊髓损伤(SCI)相关的神经源性膀胱(NB)是一个严重的健康问题。然而,尚未开发出针对NB的SCI患者的有效治疗方法。有人提出在10号染色体(PTEN)抑制剂上缺失的磷酸酶和张力蛋白同源物是诱导神经再生的有前途的选择。因此,我们研究了SCI后组织基因神经(TGN),PTEN抑制剂对排尿功能,运动功能和生长因子表达的影响。
更新日期:2020-12-05
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