The densities (ρ) and speeds of sound (u) for glycine in aqueous solutions of (0.01, 0.02, 0.03, and 0.04) mol·kg^-1 sulphathiazole drug have been measured at T = (288.15, 293.15, 298.15, 303.15 and 308.15) K, using vibrating tube digital densimeter and sound analyser Anton–Paar Model DSA - 5000. The apparent molar properties like apparent molar volume (V_φ), apparent molar adiabatic compressibility (K_φ, _s⁰) and the apparent molar volume (V_φ⁰) and adiabatic compressibility at infinite dilution (K_φ,_s ⁰) of glycine have been determined in water as well as in ternary mixtures containing sulphathiazole drug at different concentrations and at different temperatures from experimental data of densities and speeds of sound under atmospheric pressure. These data were also used to calculate the transfer parameters. Transfer parameters have been explained from the point of view of concentration dependence of solute-solute and solute-solvent interactions. The limiting apparent molar expansibility (E) values for glycine in aqueous solutions of drug have been calculated. The calculated values of thermal expansion coefficient (α₂) have small and positive values. These results are explained on the basis of drug-amino acid - water interactions and hydrophobic –hydrophilic interactions.

中文翻译：

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T =（288.15至308.15）K下磺胺噻唑药物水溶液中甘氨酸的体积和声学研究

测定了（0.01、0.02、0.03和0.04）mol·kg ^-1硫代噻唑药物在水溶液中的甘氨酸的密度（ρ）和声速（u）在T =（288.15、293.15、298.15、303.15和308.15）K，使用振动管密度计数字和声音分析器安东-帕尔模型DSA - 5000表观摩尔性能如表观摩尔体积（V _φ），表观摩尔绝热压缩（ķ _φ，_š ⁰）和表观摩尔体积（V _φ ⁰在无限稀释）和绝热压缩（ķ _φ，_{s ^} ⁰根据在大气压力下的密度和声速实验数据，已在水中以及含有不同浓度和温度的磺胺噻唑药物的三元混合物中确定了甘氨酸的含量）。这些数据还用于计算传输参数。已经从溶质-溶质和溶质-溶剂相互作用的浓度依赖性的角度解释了转移参数。已经计算出药物水溶液中甘氨酸的极限表观摩尔膨胀率（E）值。热膨胀系数的计算值（α ₂）具有较小的正值。这些结果是根据药物-氨基酸-水相互作用和疏水-亲水相互作用进行解释的。