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Synthesis, characterization and applications of Organomecury(II) pyrrolidine-N-thiohydrazide complexes
Indian Journal of Chemistry, Section A ( IF 0.412 ) Pub Date : 2020-12-03
Rama Sharma, N K Kaushik

The complexes of organomercury(II) with pyrrolidine-N-thiohydrazide of the type RHg(L)Cl where[R=C6H5 (phenyl), p-ClC6H4 (p-chlorophenyl), p-BrC6H4 (p-bromophenyl), o-, p-HOC6H4, (o-,p-hydroxyphenyl), L = pyrrolidine-N-thiohydrazide, have been synthesized and characterized by elemental analysis, IR,1H-NMR and electronic spectral analysis. Thermogravimetric and differential thermal analytical curves are used to calculate thermodynamic parameters and variations in these parameters have been correlated with complex structural parameters. All complexes were tested in vitro for their antibacterial activity against Gram-negative bacteria, namely, Escherichia coli, Zymomonas mobilis and against two pathogenic fungal strains, namely, Aspergillus niger and Cerveleria.

中文翻译:

有机汞(II)吡咯烷-N-硫酰肼配合物的合成,表征和应用

有机汞(II)与RHg(L)Cl类型的吡咯烷-N-硫代肼的配合物,其中[R = C 6 H 5(苯基),p-ClC 6 H 4(对氯苯基),p-BrC 6 H合成了4(对溴苯基),o-,p-HOC 6 H 4,(o-,对羟基苯) L =吡咯烷-N-硫代酰肼,并通过元素分析IR 1表征1 H-NMR和电子光谱分析。使用热重分析和微分热分析曲线来计算热力学参数,并且这些参数的变化已与复杂的结构参数相关联。在体外测试了所有复合物对革兰氏阴性细菌即大肠杆菌运动发酵单胞菌和对两种病原性真菌菌株黑曲霉Cerveleria的抗菌活性。
更新日期:2020-12-03
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