High-Intensity Interval Exercise (HIIE) has been shown to be more effective than moderate-intensity exercise for increasing acute lipid oxidation and lowering blood lipids during exercise and postprandially. Exercise in cold environments is also known to enhance lipid oxidation, however the immediate and long-term effects of HIIE exercise in cold are unknown. The purpose of this study was to examine the effects cold stress during HIIE on acute exercise metabolism and postprandial metabolism. Eleven recreationally active individuals (age: 23±3 years, weight: 80±9.7 kg, V̇O_2peak: 39.2±5.73 mL·kg^-1·min^-1) performed evening HIIE sessions (10x60s cycling, 90% V̇O_2peak interspersed with 90s active recovery, 30% V̇O_2peak) in thermoneutral (HIIE-TN, control; 21°C) and cold environments (HIIE-CO; 0°C), following a balanced crossover design. The following morning, participants consumed a high-fat meal. Indirect calorimetry was used to assess substrate oxidation, and venous blood samples were obtained to assess changes in noncellular metabolites. During acute exercise, lipid oxidation was 113% higher in HIIE-CO (p=0.002) without differences in V̇O₂ and EE (p≥0.162) between conditions. Postprandial V̇O₂, lipid and CHO oxidation, plasma insulin and triglyceride concentrations were not different between conditions (p>0.05). Postprandial blood LDL-C levels were higher in HIIE-CO two hours after the meal (p=0.003). Postprandial glucose AUC was 49% higher in HIIE-CO vs HIIE-TN (p=0.034). Under matched energy expenditure conditions, HIIE demonstrated higher lipid oxidation rates during exercise in the cold; but only marginally influenced postprandial lipid metabolism the following morning. In conclusion, HIIE in the cold seemed to be less favorable for postprandial lipid and glycemic responses.

中文翻译：

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高强度间歇锻炼可调节急性和餐后代谢

高强度间歇运动（HIIE）在运动中和餐后增加急性脂质氧化和降低血脂方面比中强度运动更为有效。还已知在寒冷环境中锻炼会增强脂质氧化，但是HIIE运动在寒冷中的即时和长期影响尚不清楚。这项研究的目的是检查HIIE期间的冷应激对急性运动代谢和餐后代谢的影响。十一娱乐性活性的个体（年龄：23±3岁，重量：80±9.7公斤，VO _2peak：39.2±5.73毫升公斤· ^-1 ·分钟^-1）进行晚间HIIE会话（10x60s循环，90％VO _2peak穿插90年代主动恢复，30％_V̇O2peak）在热中性（HIIE-TN，控制; 21°C）和寒冷环境（HIIE-CO; 0°C）下，采用平衡分频设计。第二天早上，参与者食用了高脂餐。间接量热法用于评估底物氧化，并获得静脉血样品以评估非细胞代谢产物的变化。在急性运动，脂质氧化是高113％在HIIE-CO（P = 0.002），而在VO差异₂和条件之间EE（p≥0.162）。餐后VO ₂，脂质和CHO氧化，血浆胰岛素和甘油三酸酯浓度在不同条件下无差异（p> 0.05）。饭后两小时，HIIE-CO的餐后血液中的LDL-C水平较高（p = 0.003）。HIIE-CO的餐后葡萄糖AUC比HIIE-TN高49％（p = 0.034）。在能量消耗匹配的情况下，HIIE在寒冷的运动过程中表现出更高的脂质氧化率。但第二天早晨仅对餐后脂质代谢产生了轻微影响。总之，感冒时的HIIE似乎对餐后脂质和血糖反应不利。