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Nickel-Catalyzed Reductive Allylation of Aldehydes with Allyl Acetates
Synthesis ( IF 2.6 ) Pub Date : 2020-12-02 , DOI: 10.1055/s-0040-1705961
Eiji Yamaguchi , Akichika Itoh , Hiroyuki Suzuki

Carbonyl allylation reactions constitute an important step in the formation of carbon–carbon reactions, and involve various related reactions that chiefly use allylmetal reagents. This report presents a nickel-catalyzed carbonyl allylation reaction using allyl acetate, which produces homoallyl alcohols in moderate to good yields, as an efficient methodology under reductive coupling conditions.



中文翻译:

镍与乙酸烯丙酯的醛催化还原烯丙基化

羰基烯丙基化反应是形成碳-碳反应的重要步骤,涉及各种主要使用烯丙基金属试剂的相关反应。该报告提出了一种使用乙酸烯丙酯的镍催化的羰基烯丙基化反应,该反应可在还原偶联条件下以中等至良好的收率生产均烯丙基醇。

更新日期:2020-12-03
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