SARS-CoV-2, the virus causing the current COVID-19 pandemic, primarily targets the airway epithelium and in lungs can lead to acute respiratory distress syndrome. Clinical studies in recent months have revealed that COVID-19 is a multi-organ disease causing characteristic complications. Stem cell models of various organ systems—most prominently, lung, gut, heart, and brain—are at the forefront of studies aimed at understanding the role of direct infection in COVID-19 multi-organ dysfunction.

中文翻译：

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使用干细胞技术模拟 SARS-CoV-2 的多器官感染

SARS-CoV-2 是导致当前 COVID-19 大流行的病毒，主要针对气道上皮，在肺部可导致急性呼吸窘迫综合征。近几个月的临床研究表明，COVID-19 是一种引起特征性并发症的多器官疾病。各种器官系统（最突出的是肺、肠道、心脏和大脑）的干细胞模型处于研究的前沿，旨在了解直接感染在 COVID-19 多器官功能障碍中的作用。