The reaction of 2-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)phenols with cyclopentanone, cyclohexanone, or 4-methylcyclohexanone gave spiro derivatives of 1,10b-dihydropyrazolo[1,5-c][1,3]benzoxazines. The antimicrobial, anti-inflammatory, and antioxidant activities of these compounds were studied. A compound with a high antimicrobial activity against S. aureus ATCC 43300, together with compounds possessing an anti-inflammatory effect superior to the reference drug diclofenac, as well as high antioxidant activity, were identified.

中文翻译：

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1,10b-二氢-5 H-吡唑并[1,5-c] [1,3]-苯并恶嗪的螺衍生物及其抗菌，抗炎和抗氧化活性

2-（3-芳基-4,5-二氢-1 H-吡唑-5-基）酚与环戊酮，环己酮或4-甲基环己酮的反应生成1,10b-二氢吡唑并[1,5- c]的螺衍生物] [1,3]苯并恶嗪。研究了这些化合物的抗微生物，抗炎和抗氧化活性。鉴定了对金黄色葡萄球菌ATCC 43300具有高抗菌活性的化合物，以及具有优于参考药物双氯芬酸的抗炎作用以及高抗氧化活性的化合物。