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Bi-Stability of a Pyramidal Structure of NH2 Groups in Nitrous Bases and its Role in the Structural and Functional Organization of the Genomic DNA
Russian Physics Journal ( IF 0.6 ) Pub Date : 2020-12-01 , DOI: 10.1007/s11182-020-02175-4
V. M. Komarov , A. A. Samchenko

The influence of the stable sp3 hybrid structure of the valence amino group orbitals of nitrous bases on the initiation of the hidden structural polymorphism of the Watson–Crick base pairs is considered. The key role of differences in the polymorphism of the AT and GC pairs in the formation of structural and functional features of the genomic DNA is shown by the methods of computer chemistry and comparative genomics.

中文翻译:

亚硝酸基中 NH2 基团金字塔结构的双稳定性及其在基因组 DNA 结构和功能组织中的作用

考虑了亚硝基价氨基轨道的稳定 sp3 杂化结构对 Watson-Crick 碱基对隐藏结构多态性起始的影响。AT 和 GC 对的多态性差异在基因组 DNA 结构和功能特征形成中的关键作用通过计算机化学和比较基因组学的方法显示出来。
更新日期:2020-12-01
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