Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gasses. An acute exacerbation of COPD refers to a flare up or episode where a person breathing becomes worse than normal. An acute exacerbation of COPD refers to a flare up or episode where a person breathing becomes worse than normal. Acute exacerbation in COPD (AECOPD) is frequent in the course of the illness and is the most common reason for medical visits, hospital admissions, and mortality among these patients. Exacerbations of COPD are associated with increased morbidity and mortality. To assess the exposure and severity of acute exacerbations of COPD with COPD Assessment Test (CAT Scale) and mMRC (modified Medical Research Council) Dyspnea scale. Study design was a hospital-based prospective observational study. Study site was conducted at Pulmonology Department of Government General Hospital, Vijayawada. The total patients were 197. Out of which, 119 were from In-patient Department (IPD) and 78 were from Out-patient Department (OPD). In this study, males were 167 (85%), among which, IPD were 97 (49%), OPD were 70 (36%), and females were 30 (15%), among which, IPD were 22 (11%), OPD were 8 (4%). The morbidity and mortality of COPD have been increased in recent years. This study concludes that there is a relation between risk of acute exacerbations in COPD with habitual history and occupational history. Increase in exposure to occupational hazards, smoking habit leads to an increase in risk of acute exacerbations in COPD patients. The level of severity was more in smokers and the patients who had biomass, organic dust, and mineral exposure. When severity was observed, group D severity is more observed in population according to CAT scale and mMRC dyspnea scale.

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三级医院肺内科对慢性阻塞性肺疾病急性加重的前瞻性观察研究

慢性阻塞性肺疾病（COPD）是一种常见，可预防和可治疗的疾病，其特征在于持续的呼吸道症状和气流受限，这是由于气道和/或肺泡异常所致，通常是由于大量暴露于有害颗粒或气体引起的。COPD的急性加重是指突然发作或发作，使人的呼吸变得比正常情况差。COPD的急性加重是指突然发作或发作，使人的呼吸变得比正常情况差。COPD急性加重（AECOPD）在疾病过程中很常见，并且是这些患者就诊，住院和死亡率最高的最常见原因。COPD的恶化与发病率和死亡率增加有关。用COPD评估测试（CAT量表）和mMRC（改良医学研究委员会）呼吸困难量表评估COPD急性发作的暴露程度和严重程度。研究设计是基于医院的前瞻性观察性研究。研究地点在维杰亚瓦达州政府总医院肺科进行。共有197名患者。其中，119名来自住院部（IPD），78名来自门诊部（OPD）。在这项研究中，男性为167（85％），其中IPD为97（49％），OPD为70（36％），女性为30（15％），其中IPD为22（11％） ，OPD为8（4％）。近年来，COPD的发病率和死亡率增加了。本研究的结论是，COPD急性加重的风险与习惯病史和职业病史之间存在关联。接触职业危害，吸烟习惯的机​​会增加，导致COPD患者急性发作的风险增加。吸烟者以及有生物质，有机粉尘和矿物质暴露的患者的严重程度更高。当观察到严重程度时，根据CAT量表和mMRC呼吸困难量表，在人群中观察到D组严重程度更高。