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Current diagnostic tools and management modalities of Nocardia keratitis
Journal of Ophthalmic Inflammation and Infection Pub Date : 2020-12-02 , DOI: 10.1186/s12348-020-00228-w
Mohammad Soleimani , Ahmad Masoumi , Sadegh Khodavaisy , Mostafa Heidari , Ali A. Haydar , Alireza Izadi

Nocardia species are an uncommon but important cause of keratitis. The purpose of this review is to discus previous published papers relation to the epidemiology, etiology, diagnosis and management of Nocardia keratitis. Nocardia asteroides is the most frequently reported from Nocardia keratitis. Pain, photophobia, blepharospasm and lid swelling are mainly clinical manifestations. Usual risk factors for Nocardia keratitis are trauma, surgery, corticosteroids, and contact lens wear. Several antibiotics were used for treatment of Nocardia infection but according to studies, topical amikacin is the drug of choice for Nocardia keratitis. Topical steroid should not prescribe in these patients. In conclusion, although Nocardia keratitis is rare, early diagnosis and treatment are essential to prevent any scar formation and preserve a good visual acuity.

中文翻译:

诺卡氏性角膜炎的当前诊断工具和管理方式

诺卡氏菌是角膜炎的罕见但重要原因。这篇综述的目的是讨论先前发表的有关诺卡氏性角膜炎的流行病学,病因学,诊断和治疗的论文。诺卡氏性角膜炎最常报道诺卡氏小行星。疼痛,畏光,眼睑痉挛和眼睑肿胀主要是临床表现。诺卡氏菌性角膜炎的常见危险因素是外伤,手术,皮质类固醇和隐形眼镜佩戴。几种抗生素已用于治疗诺卡氏菌感染,但根据研究,局部用丁胺卡那霉素是诺卡氏菌性角膜炎的首选药物。这些患者不宜使用局部类固醇。总之,尽管诺卡氏性角膜炎很少见,但早期诊断和治疗对于防止任何疤痕形成并保持良好的视力至关重要。
更新日期:2020-12-02
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