Establish the variability of C-reactive protein (CRP) within a population of first-generation immigrants living in the United States. Prior work has theorized that individuals with high levels of childhood pathogen exposure may have lower CRP levels in adulthood, and therefore that for these individuals, CRP may not be as accurate an index of chronic disease risk related to low-level inflammation as is presumed based on data from wealthy populations. This potentially has major implications for the interpretation of CRP as a biomarker of chronic inflammation.

中文翻译：

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居住在美国的第一代厄瓜多尔移民中 C 反应蛋白的变异性

确定居住在美国的第一代移民人群中 C 反应蛋白 (CRP) 的变异性。先前的研究认为，儿童期病原体暴露水平高的个体在成年期可能具有较低的 CRP 水平，因此对于这些个体，CRP 可能不像基于假设的那样准确地作为与低水平炎症相关的慢性病风险指数来自富裕人群的数据。这可能对将 CRP 解释为慢性炎症的生物标志物具有重要意义。