Substance Use Disorder (SUD) is a chronic and relapsing disease characterized by craving, loss of control, tolerance and physical dependence. At present, the combination of pharmacotherapy and psychosocial intervention is the most effective management strategy in preventing relapse to reduce dropout rates and promote abstinence in SUD patients. However, only few effective medications are available. Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation technique that modulates the cellular activity of the cerebral cortex through a magnetic pulse applied on selected brain areas. Recently, the efficacy of TMS has been investigated in various categories of SUD patients. The present review analyzes the application of repetitive TMS in patients with alcohol, tobacco, and cocaine use disorder. Although the number of clinical studies is still limited, repetitive TMS yields encouraging results in these patients, suggesting a possible role of TMS in the treatment of SUD.

物质使用障碍（SUD）是一种慢性且复发性疾病，其特征是渴望，失去控制，耐受力和身体依赖性。目前，药物治疗和社会心理干预相结合是预防SUD患者复发，降低辍学率和促进戒酒的最有效管理策略。但是，只有几种有效的药物可供使用。经颅磁刺激（TMS）是一种非侵入性的脑刺激技术，通过施加在选定的大脑区域上的磁脉冲来调节大脑皮层的细胞活动。最近，已经在各种类别的SUD患者中研究了TMS的疗效。本综述分析了重复性TMS在酒精，烟草和可卡因使用障碍患者中的​​应用。