Bacterial wilt caused by the Ralstonia solanacearum species complex (RSSC) threatens the cultivation of important crops worldwide. We sequenced 30 RSSC phylotype I ( R. pseudosolanacearum ) strains isolated from pepper (Capsicum annuum) and tomato (Solanum lycopersicum) across the Republic of Korea. These isolates span the diversity of phylotype I, have extensive effector repertoires and are subject to frequent recombination. Recombination hotspots among South Korean phylotype I isolates include multiple predicted contact-dependent inhibition loci, suggesting that microbial competition plays a significant role in Ralstonia evolution. Rapid diversification of secreted effectors presents challenges for the development of disease-resistant plant varieties. We identified potential targets for disease resistance breeding by testing for allele-specific host recognition of T3Es present among South Korean phyloype I isolates. The integration of pathogen population genomics and molecular plant pathology contributes to the development of location-specific disease control and development of plant cultivars with durable resistance to relevant threats.

中文翻译：

---

宿主适应和微生物竞争驱动韩国青枯病菌系统型 I 的进化

由青枯病菌物种复合体 (RSSC)引起的青枯病威胁着全球重要作物的种植。我们对从韩国辣椒 ( Capsicum annuum ) 和番茄 ( Solanum lycopersicum ) 中分离的30 个 RSSC 系统发育型 I ( R. pseudosolanacearum ) 菌株进行了测序。这些分离株跨越了系统发育型 I 的多样性，具有广泛的效应库，并且经常发生重组。韩国系统发育型 I 分离株的重组热点包括多个预测的接触依赖性抑制位点，表明微生物竞争在Ralstonia 中起着重要作用 进化。分泌效应物的快速多样化给抗病植物品种的开发带来了挑战。我们通过测试韩国 phyloype I 分离株中存在的 T3E 的等位基因特异性宿主识别，确定了抗病育种的潜在目标。病原体种群基因组学和分子植物病理学的整合有助于特定地点疾病控制的发展和对相关威胁具有持久抗性的植物品种的发展。