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3D multi-view tumor detection in automated whole breast ultrasound using deep convolutional neural network
Expert Systems with Applications ( IF 8.5 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.eswa.2020.114410
Yue Zhou , Houjin Chen , Yanfeng Li , Shu Wang , Lin Cheng , Jupeng Li

In recent years, automated whole breast ultrasound (ABUS) has drawn attention to breast disease detection and diagnosis applications. However, reviewing ABUS volumes is a time-costing task and some subtle tumors may be missed. In this paper, a 3D multi-view tumor detection method is proposed for ABUS volumes. Firstly, a layer connected feature extraction network is designed for Faster R-CNN. Then, orthogonal multi-view slices are reconstructed and detected using this modified Faster R-CNN to extract 2D candidates. Finally, a 3D multi-view position analysis scheme is designed to fuse 2D detection results and get final 3D bounding boxes. The performance of this proposed method is evaluated on a data set of 158 volumes from 75 patients by 5-fold cross-validation. Experimental results show that our method achieves a sensitivity of 95.06% with 0.57 false positives (FPs) per volume. Compared with existing detection methods, the proposed method is more effective and general.



中文翻译:

使用深度卷积神经网络的自动化全乳超声3D多视图肿瘤检测

近年来,自动全乳超声(ABUS)已引起人们对乳腺疾病检测和诊断应用的关注。但是,检查ABUS量是一项耗时的工作,并且可能会漏掉一些细微的肿瘤。本文提出了一种针对ABUS体积的3D多视图肿瘤检测方法。首先,为Faster R-CNN设计了一个层连接的特征提取网络。然后,使用此修改后的Faster R-CNN重建并检测正交多视图切片,以提取2D候选对象。最后,设计了一种3D多视图位置分析方案,以融合2D检测结果并获得最终的3D边界框。通过5倍交叉验证,在来自75位患者的158卷数据集上评估了此提议方法的性能。实验结果表明,我们的方法在0时达到了95.06%的灵敏度。每卷57个误报(FP)。与现有的检测方法相比,该方法更有效,更通用。

更新日期:2020-12-05
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