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KiMoSys 2.0: an upgraded database for submitting, storing and accessing experimental data for kinetic modeling
Database: The Journal of Biological Databases and Curation ( IF 5.8 ) Pub Date : 2020-11-28 , DOI: 10.1093/database/baaa093
Hugo Mochão 1 , Pedro Barahona 2 , Rafael S Costa 3, 4
Affiliation  

The KiMoSys (https://kimosys.org), launched in 2014, is a public repository of published experimental data, which contains concentration data of metabolites, protein abundances and flux data. It offers a web-based interface and upload facility to share data, making it accessible in structured formats, while also integrating associated kinetic models related to the data. In addition, it also supplies tools to simplify the construction process of ODE (Ordinary Differential Equations)-based models of metabolic networks. In this release, we present an update of KiMoSys with new data and several new features, including (i) an improved web interface, (ii) a new multi-filter mechanism, (iii) introduction of data visualization tools, (iv) the addition of downloadable data in machine-readable formats, (v) an improved data submission tool, (vi) the integration of a kinetic model simulation environment and (vii) the introduction of a unique persistent identifier system. We believe that this new version will improve its role as a valuable resource for the systems biology community.

中文翻译:

KiMoSys 2.0:用于提交、存储和访问动力学建模实验数据的升级数据库

KiMoSys (https://kimosys.org) 于 2014 年推出,是已发布实验数据的公共存储库,其中包含代谢物的浓度数据、蛋白质丰度和通量数据。它提供了一个基于网络的界面和上传工具来共享数据,使其以结构化格式访问,同时还集成了与数据相关的相关动力学模型。此外,它还提供工具来简化基于 ODE(常微分方程)的代谢网络模型的构建过程。在此版本中,我们展示了 KiMoSys 的更新,其中包含新数据和多项新功能,包括 (i) 改进的 Web 界面,(ii) 新的多过滤器机制,(iii) 引入数据可视化工具,(iv)添加机器可读格式的可下载数据,(v) 改进的数据提交工具,(vi) 整合动力学模型模拟环境和 (vii) 引入唯一的持久标识符系统。我们相信这个新版本将改善其作为系统生物学界宝贵资源的作用。
更新日期:2020-12-01
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