OBJECTIVE To assess the relationship between generalized convulsive status epilepticus (GCSE) during an index stroke hospitalization and occurrence of 30-day hospital readmission. METHODS Retrospective analysis of data within the 2014 National Readmission Database, a national dataset tracking readmissions in the United States. We identified patients with an index discharge diagnosis of stroke using the International Classification of Disease, Ninth Revision, Clinical Modification (433.X1, 434.X1, and 436 for ischemic stroke and 430, 431, 432.0, 432.1, and 432.9 for hemorrhagic stroke) and a subset of patients with GCSE (345.3). We explored the association between GCSE and 30-day readmission using multivariable logistic regression, while applying recommended survey weights. RESULTS Of 271,148 adults with a primary diagnosis of stroke hospitalizations in the US in 2014, 591 (0.21%) had GCSE. The prevalence of GCSE was 0.14% among ischemic stroke patients and 0.64% among hemorrhagic stroke patients. Readmission rates were 11.9% for all strokes, 11.6% for ischemic strokes, and 14.2% for hemorrhagic strokes. Readmission rates were significantly higher for those with GCSE vs. without GCSE regardless of stroke type. Adjusted odds ratios for the association of GCSE with 30-day readmission were 1.30 (95% CI: 1.02-1.65) for all strokes, 1.19 (95% CI: 0.84-1.71) for ischemic strokes, and 1.39 (95% CI: 0.92-2.10 0.09) for hemorrhagic stroke. CONCLUSION Approximately one in eight hospitalized stroke patients who experience in-hospital GCSE are re-admitted to a hospital within 30 days with a nominally higher rate of readmissions among those with hemorrhagic stroke.

中文翻译：

---

卒中住院期间全身性癫痫持续状态后早期再入院

目的 评估卒中指数住院期间全身性惊厥性癫痫持续状态 (GCSE) 与 30 天再入院率之间的关系。方法 对 2014 年国家再入院数据库中的数据进行回顾性分析，这是一个跟踪美国再入院的国家数据集。我们使用国际疾病分类第九版临床修正（缺血性卒中为 433.X1、434.X1 和 436，出血性卒中为 430、431、432.0、432.1 和 432.9）识别出中风指数出院诊断的患者) 和一部分 GCSE 患者 (345.3)。我们使用多变量逻辑回归探索了 GCSE 与 30 天再入院之间的关联，同时应用了推荐的调查权重。结果 271, 2014 年美国有 148 名初步诊断为卒中住院的成年人，其中 591 人 (0.21%) 获得了 GCSE。GCSE 的患病率在缺血性卒中患者中为 0.14%，在出血性卒中患者中为 0.64%。所有卒中的再入院率为 11.9%，缺血性卒中的再入院率为 11.6%，出血性卒中的再入院率为 14.2%。无论卒中类型如何，GCSE 患者的再入院率均显着高于 GCSE 患者。GCSE 与 30 天再入院相关性的调整优势比对于所有卒中为 1.30（95% CI：1.02-1.65），对于缺血性卒中为 1.19（95% CI：0.84-1.71）和 1.39（95% CI：0.92） -2.10 0.09) 用于出血性中风。