This paper presents the results of the research on the influence of catalytic activity of iron(II) octacarboxyphthalocyanines (FePcOC) on the transformation of diclofenac (DCF) which is the most popular anti-inflammatory analgesic. Diclofenac poses a serious threat to the natural environment. The paper demonstrates that diclofenac, in the presence a monomeric form of iron octacarboxyphthalocyanine and hydroxyl radicals (HO^•) (from H₂O₂), undergoes a transformation into diclofenac-2,5-iminoquinone (DCF-2,5-IQ), causing distinct changes in the UV-Vis absorption spectrum. In the presence of iron octacarboxyphthalocyanine and H₂O₂, the previously colourless diclofenac solution becomes intense orange. As a result, a new band at approx. 450 nm appears in the absorption spectrum. HPLC analysis has shown that the concentration of diclofenac decreases with time. TD-DFT calculations using the CAM-B3LYP/6-31+G (d, p) method have been conducted to confirm experimental data concerning the formation of a new band at λ_max = 450 nm.

本文介绍了八价铁酞菁铁（IIP）催化活性对最受欢迎的消炎镇痛药双氯芬酸（DCF）转化的影响的研究结果。双氯芬酸对自然环境构成了严重威胁。本文证明双氯芬酸在八价羧基酞菁铁和羟基自由基（HO ^•）（来自H ₂ O ₂）的单体形式下，转化为双氯芬酸-2,5-亚氨基醌（DCF-2,5-IQ） ，导致UV-Vis吸收光谱发生明显变化。在八羧基酞菁铁和H ₂ O ₂存在下，以前无色的双氯芬酸溶液变成深橙色。结果，大约有一个新的乐队。450nm出现在吸收光谱中。HPLC分析表明双氯芬酸的浓度随时间降低。进行了使用CAM-B3LYP / 6-31 + G（d，p）方法的TD-DFT计算，以确认有关在_λmax = 450 nm处形成新谱带的实验数据。