Dual Catalytic Strategy for Forging sp2–sp3 and sp3–sp3 Architectures via β-Scission of Aliphatic Alcohol Derivatives,Journal of the American Chemical Society

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Dual Catalytic Strategy for Forging sp2–sp3 and sp3–sp3 Architectures via β-Scission of Aliphatic Alcohol Derivatives
Journal of the American Chemical Society ( IF 15.0 ) Pub Date : 2020-11-30 , DOI: 10.1021/jacs.0c11172
Fei Cong _{1,

2} , Xin-Yang Lv _{1,

2} , Craig S. Day _{1,

2} , Ruben Martin _{1,

3}

Affiliation

A dual platform for forging sp2-sp3 and sp3-sp3 carbon bonds via catalytic β-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. This protocol is distinguished by its wide substrate scope and broad applicability, even in the context of late-stage functionalization.

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