当前位置: X-MOL 学术Nat. Neurosci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Natural killers of cognition
Nature Neuroscience ( IF 25.0 ) Pub Date : 2020-11-30 , DOI: 10.1038/s41593-020-00749-6
Nurit Papismadov 1 , Valery Krizhanovsky 1
Affiliation  

One of the mechanisms driving aging and neurodegenerative diseases is the accumulation of senescent cells, while their elimination mitigates age-related decline. A new report details how, with aging, changes in the dentate gyrus microenvironment lead to natural-killer-cell-mediated clearance of neurogenic senescent cells, resulting in cognitive decline.

中文翻译:

认知的自然杀手

导致衰老和神经退行性疾病的机制之一是衰老细胞的积累,而它们的消除可以减轻与年龄相关的衰退。一份新报告详细介绍了随着年龄的增长,齿状回微环境的变化如何导致自然杀伤细胞介导的神经源性衰老细胞的清除,从而导致认知能力下降。
更新日期:2020-12-01
down
wechat
bug