Abstract

A polyaspartamide containing both hydroxyl and amine pendants, PolyAspAm(EA/EDA), was prepared. Upon mixing PolyAspAm(EA/EDA) with tannic acid (TA) in an aqueous solution, a viscous complex gel or precipitates are formed, where the complexation behavior is influenced by composition, pH, and temperature. The reversible phase change depending on pH and temperature suggested that the complex gel formation be driven by physical bonding, mainly hydrogen bonding. TA, a plant-derived polyphenolic compound, was used as gelator and adhesion promoter. The adhesive and antibacterial properties of complex gels are discussed. This polyaspartamide/TA based physical gel has potential as a stimuli-responsive and biocompatible adhesive.

摘要

制备了含有羟基和胺侧基的聚天冬酰胺，PolyAspAm(EA/EDA)。在水溶液中将聚天冬氨酸 (EA/EDA) 与单宁酸 (TA) 混合后，会形成粘性复合凝胶或沉淀物，其中复合行为受组成、pH 和温度的影响。取决于 pH 和温度的可逆相变表明复杂凝胶的形成是由物理键合驱动的，主要是氢键合。TA，一种植物衍生的多酚化合物，被用作凝胶剂和粘合促进剂。讨论了复合凝胶的粘合和抗菌性能。这种基于聚天冬酰胺/TA 的物理凝胶具有作为刺激响应和生物相容性粘合剂的潜力。