Jackfruit mucilage (JM) obtained from the fruit, Artocarpus heterophyllus was melt blended with poly(ε‐caprolactone) (PCL). The physical properties of the blends with more than 60 wt% PCL were investigated. Depression in the equilibrium melting temperature ( $T_m^o$) and the presence of extinction rings in the spherulites of PCL in the blends confirmed miscibility of the two components. The carbonyl and the COC groups of PCL and JM were responsible for the interactions as identified by Fourier transform infrared spectroscopy. The thermal stability of PCL decreased marginally in the blends with increasing JM content. The scanning electron microscopy (SEM) images indicated that no phase separation occurred. Porosity and the mechanical strength of the blends decreased with increasing JM content. Blends exposed to porcine pancreatic lipase showed enzymatic degradation of JM but not PCL and SEM images showed holes in the sample indicative of selective degradation of JM. Cell growth inhibition technique using the L929 fibroblasts cells showed the degree of inhibition was dependent on the increasing JM content in the blends. Blends with low JM content have the potential to be used for increased cell viability while blends with high JM content can be used for the treatment of cancer.

中文翻译：

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用于组织工程应用的聚（ε-己内酯）-“波罗蜜”粘液混合物的表征和体外分析

将从果实（Artocarpus heterophyllus）获得的菠萝蜜（JM）与聚（ε-己内酯）（PCL）熔融共混。研究了具有超过60 wt％PCL的共混物​​的物理性能。平衡熔融温度降低（${Ť}_{米}^{Ø}$）和混合物中PCL球晶中的消光环证实了这两种组分的混溶性。羰基以及C  Ò C组PCL和JM负责通过傅立叶变换红外光谱法鉴定的相互作用。随着JM含量的增加，共混物中PCL的热稳定性略有下降。扫描电子显微镜（SEM）图像表明没有相分离发生。共混物的孔隙率和机械强度随JM含量的增加而降低。暴露于猪胰脂肪酶的混合物显示酶降解JM，但未显示PCL，SEM图像显示样品中出现孔，表明JM选择性降解。使用L929成纤维细胞的细胞生长抑制技术表明抑制程度取决于混合物中JM含量的增加。