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Front Cover: Rapid Access to Dispirocyclic Scaffolds Enabled by Diastereoselective Intramolecular Double Functionalization of Benzene Rings (Chem. Asian J. 24/2020)
Chemistry - An Asian Journal ( IF 4.1 ) Pub Date : 2020-11-30 , DOI: 10.1002/asia.202001313
Hiromasa Yokoe 1 , Yuka Mizumura 1 , Kana Sugiyama 1 , Kejia Yan 1 , Yuna Hashizume 1 , Yuto Endo 1 , Sae Yoshida 1 , Akiko Kiriyama 1 , Masayoshi Tsubuki 1 , Naoki Kanoh 1
Affiliation  

There is an Asian legend in which a fish climbs over a waterfall and turns into a dragon. In this study, domino double spirocyclization occurred over the high energy barrier arising from the aromaticity. The key reagents were Ag salt, N‐iodosuccinimide (NIS), and 1,1,1,3,3,3‐hexafluoro‐2‐propanol (HFIP) solvent, whose names are hidden in the picture. These reagents transformed simple molecules into complex 3D architectures. More information can be found in the Communication by Hiromasa Yokoe, Naoki Kanoh et al.
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中文翻译:

封面:通过苯环的非对映选择性分子内双官能团实现的对双螺环骨架的快速访问(Chem。Asian J. 24/2020)

有亚洲传说,一条鱼爬过瀑布变成一条龙。在这项研究中,多米诺骨牌双螺环化发生在由芳香性引起的高能垒之上。关键试剂为银盐,N-碘代琥珀酰亚胺(NIS)和1,1,1,3,3,3-六氟-2-丙醇(HFIP)溶剂,其名称隐藏在图片中。这些试剂将简单分子转化为复杂的3D体系结构。有关更多信息,请参见Hiromasa Yokoe的通讯,Naoki Kanoh等人的文章。
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更新日期:2020-12-16
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