It was established that roots of Ammothamnus lehmannii should be extracted with EtOH (90%) at room temperature at least five times for effective extraction of total flavonoids from them. At least five extractions with BuOH of the bottom residue of the A. lehmannii extract were necessary for almost complete extraction of total flavonoids from it. Conditions for isolation of flavonoids were determined and included dissolution of the crude product in alkaline solution (3%) followed by acidification to pH 5.0 – 7.0. A technological scheme for isolation of a drug composition consisting of total flavonoids from A. lehmannii roots was developed. Aspectrophotometric method for quantitative determination of the resulting total flavonoids was proposed. Total flavonoids isolated from A. lehmannii roots had a pronounced anthelmintic effect with anticestodal activity exceeding that of the pure flavonoid ammothamnidine and could be recommended as a potential effective antiparasitic drug.

中文翻译：

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沙门冬虫属蠕虫药的生产工艺

已经确定，应在室温下用 EtOH (90%) 提取沙门冬青的根至少 5 次，以有效地从中提取总黄酮。莱曼木霉提取物的底部残留物至少需要用 BuOH 提取五次，才能从其中几乎完全提取总黄酮类化合物。确定了黄酮类化合物的分离条件，包括将粗产物溶解在碱性溶液 (3%) 中，然后酸化至 pH 值 5.0 – 7.0。开发了一种从莱曼木香根中分离由总黄酮组成的药物组合物的技术方案。提出了用于定量测定所得总黄酮的分光光度法。从 A. 中分离出的总黄酮类化合物。