β-glucan from Lentinus edodes(LNT) is a plant-derived medicinal fungus possessing significant bioactivities on anti-tumor. Both hypoxia-induced factor-1α (HIF)-1α and Nur77 have been shown to be involved in the development of breast cancer. However, there is yet no proof of Nur77/HIF-1α involvement in the process of LNT-mediated tumor-inhibition effect.

中文翻译：

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香菇中的β-葡聚糖通过Nur77 /HIF-1α轴抑制乳腺癌的进展。

香菇（LNT）的β-葡聚糖是一种植物来源的药用真菌，在抗肿瘤方面具有重要的生物活性。缺氧诱导因子-1α（HIF）-1α和Nur77已被证明与乳腺癌的发生有关。但是，尚无Nur77 /HIF-1α参与LNT介导的肿瘤抑制作用过程的证据。