This paper presents a novel method to prevent blockages by embolic microspheres in catheter channels by using convex air bubbles attached to the channels’ inner wall surface. The clogging by microspheres can occur by the arching of the microspheres in the catheter. A few studies have been done on reducing the blockage, but their methods are not suitable for use with embolic catheters. In this study, straight catheter channels were fabricated. They had cavities to form convex air bubbles; additionally, a straight channel without the cavities was designed for comparison. Blockage was observed in the straight channel without the cavities, and the blockage arching angle was measured to be 70°, while no blockage occurred in the cavity channel with air bubbles, even at a geometrical arching angle of 85°. The convex air bubbles have an important role in preventing blockages by microspheres. The slip effect on the air bubble surface and the centrifugal effect make the microspheres drift away from the channel wall. It was observed that as the size of the cavity was increased, the drift distance became larger. Additionally, as more convex air bubbles were formed, the amount of early drift to the center increased. It will be advantageous to design a catheter with large cavities that have a small interval between them.

中文翻译：

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使用凸形气泡防止导管中的微球堵塞

本文提出了一种新方法，通过使用附着在通道内壁表面的凸泡来防止导管通道中的栓塞微球堵塞。微球的堵塞可通过导管中微球的拱形发生。在减少阻塞方面已经进行了一些研究，但是它们的方法不适用于栓塞导管。在这项研究中，制造了笔直的导管通道。他们有空腔形成凸出的气泡。此外，还设计了没有空腔的直通道进行比较。在没有空腔的直通道中观察到堵塞，堵塞拱形角测得为70°，而即使在85°的几何拱形角下，在空腔通道中也没有气泡发生堵塞。凸起的气泡在防止微球阻塞方面具有重要作用。气泡表面上的滑移效应和离心效应使微球漂移离开通道壁。观察到随着腔尺寸的增加，漂移距离变大。另外，随着形成更多的凸气泡，向中心的早期漂移量增加。设计具有大空腔的导管之间的间隔较小将是有利的。到中心的早期漂移量增加了。设计具有大空腔的导管之间的间隔较小将是有利的。到中心的早期漂移量增加了。设计具有大空腔的导管之间的间隔较小将是有利的。