ABSTRACT

In the present study, the effects of Eu content and sintering temperature on microstructural development and in vitro bioactive characteristic of Eu-doped monticellite-based ceramics prepared using boron derivative waste were investigated. Spherical closed porosities with a diameter below 20 μm were observed on cross-section of all ceramics. The increment of Eu content from 1% to 10% resulted in narrower size distribution of closed porosities. The increasing of sintering temperature from 900°C to 1000°C allowed amorphisation of crystalline phases and the replacement of them into porosities. In vitro bone-like apatite formation ability altered by surface feature and sintering temperature, regardless of Eu content. The ceramics sintered at 1000°C for 2 h have desired bioactive response allowing formation of dense bone-like apatite layer on the surface. Therefore, 10% Eu-doped monticellite-based ceramics achieved in an eco-friendly route have potential to be used as multifunctional bone graft substitutes for biolabeling applications.

摘要

在本研究中，研究了Eu含量和烧结温度对使用硼衍生物废料制备的Eu掺杂蒙脱石基陶瓷的微观结构发展和体外生物活性特性的影响。在所有陶瓷的横截面上观察到直径小于20 μm的球形封闭孔隙。Eu 含量从 1% 增加到 10% 导致闭合孔隙的尺寸分布变窄。烧结温度从 900°C 升高到 1000°C 允许晶相非晶化并将它们替换为孔隙。体外骨状磷灰石的形成能力随表面特征和烧结温度的变化而变化，与 Eu 含量无关。在 1000°C 下烧结 2 小时的陶瓷具有所需的生物活性反应，允许在表面形成致密的骨状磷灰石层。因此，以环保路线实现的 10% Eu 掺杂的蒙脱石基陶瓷具有用作生物标记应用的多功能骨移植替代品的潜力。