当前位置：
X-MOL 学术
›
ChemBioChem
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Front Cover: Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography (ChemBioChem 24/2020)
ChemBioChem ( IF 3.2 ) Pub Date : 2020-11-27 , DOI: 10.1002/cbic.202000778 Thomas N. G. Handley 1 , Conan K. Wang 1 , Peta J. Harvey 1 , Nicole Lawrence 1 , David J. Craik 1
ChemBioChem ( IF 3.2 ) Pub Date : 2020-11-27 , DOI: 10.1002/cbic.202000778 Thomas N. G. Handley 1 , Conan K. Wang 1 , Peta J. Harvey 1 , Nicole Lawrence 1 , David J. Craik 1
Affiliation
|
Cyclotides are a fascinating class of macrocyclic plant peptides that contain a cyclic cystine knot, a compact and highly stable structural motif. This review by D. J. Craik and co‐authors is an historical overview of the developments in NMR spectroscopy, as well as X‐ray crystallography, that have enabled the resolution of cyclotide structures and conclusive determination of disulfide connectivities of several exemplar cyclotides. Such work has been inspired by the innovative and pioneering studies of Professor Horst Kessler in cyclic peptide chemistry and NMR spectroscopy. Cover art by P.J.H.
中文翻译：
封面：通过NMR显示的环核苷酸结构，X射线晶体学的帮助很小（ChemBioChem 24/2020）
环肽是一类引人入胜的大环植物肽，包含环胱氨酸结，紧密而高度稳定的结构基序。D. J. Craik和合著者的这篇综述是NMR光谱学以及X射线晶体学的发展的历史综述，这些进展使得能够解析环化物结构并最终确定几种示例性环化物的二硫键连接性。霍斯特·凯斯勒（Horst Kessler）教授在环肽化学和NMR光谱学方面的创新和开创性研究激发了这项工作。PJH的封面艺术
更新日期：2020-12-12
中文翻译：
封面：通过NMR显示的环核苷酸结构，X射线晶体学的帮助很小（ChemBioChem 24/2020）
环肽是一类引人入胜的大环植物肽，包含环胱氨酸结，紧密而高度稳定的结构基序。D. J. Craik和合著者的这篇综述是NMR光谱学以及X射线晶体学的发展的历史综述，这些进展使得能够解析环化物结构并最终确定几种示例性环化物的二硫键连接性。霍斯特·凯斯勒（Horst Kessler）教授在环肽化学和NMR光谱学方面的创新和开创性研究激发了这项工作。PJH的封面艺术
京公网安备 11010802027423号