Abstract The Biosilicate® glass-ceramic is one of the most promising alternatives to the 45S5 Bioglass® in terms of bioactivity, osteoconductivity, osteoinductivity, non-cytotoxicity, and antibacterial properties, with significant advantages in the manufacturing of specific components of complex shapes for bone tissue application. Unlike in 45S5 glass, the crystallization does not lead to a degradation of bioactivity. In the present paper, we explored the suitability of Biosilicate® for the manufacturing of highly porous scaffolds (porosity of 50–80 vol%) by using modern additive manufacturing technologies, such as direct ink writing (DIW) and digital light processing (DLP). Both techniques could be easily applied to fine powders of Biosilicate® mixed with fugitive binders. Significant densification of the struts, despite the limited powder packing, could be achieved using liquid-assisted sintering, in turn, triggered by the phosphate-enriched residual glass phase, already at 1000 °C. The strength-to-density ratio could be variously tuned (from 1.5 to 9.5 MPa cm3/g), especially with DLP-derived samples, by adjusting both the firing temperature and the scaffold topology.

中文翻译：

---

生物硅酸盐®微晶玻璃粉末在增材制造高孔支架中的适用性

摘要 就生物活性、骨传导性、骨诱导性、非细胞毒性和抗菌性能而言，Bio硅酸盐®微晶玻璃是 45S5 Bioglass® 最有前景的替代品之一，在制造复杂形状的骨的特定组件方面具有显着优势。组织应用。与 45S5 玻璃不同，结晶不会导致生物活性降低。在本论文中，我们通过使用现代增材制造技术，如直接墨水书写 (DIW) 和数字光处理 (DLP)，探讨了生物硅酸盐® 在制造高孔隙率支架（孔隙率为 50–80 vol%）方面的适用性. 这两种技术都可以很容易地应用于与临时粘合剂混合的 Biosilitate® 细粉。支柱显着致密化，尽管粉末填充有限，但可以使用液体辅助烧结来实现，反过来，由富含磷酸盐的残留玻璃相触发，已经在 1000 °C。通过调整烧制温度和支架拓扑结构，可以对强度密度比进行各种调整（从 1.5 到 9.5 MPa cm3/g），尤其是对于 DLP 衍生的样品。