With an increase in foodborne illnesses associated with the consumption of fresh produce, it is important to understand the interactions between human bacterial enteric pathogens and plants. It was previously established that diseased plants can create a permissive environment for opportunistic endophytic colonization of enteric pathogens. However, the factors that contribute to the colonization of enteric pathogens during plant disease are largely unknown. Here, we show that both strain and plant host factors contribute to significantly increased populations of enteric pathogens when co-inoculated with the plant pathogen, P. syringae pv. tomato. The two Salmonella enterica strains DM10000 and 14028S, differ in their ability to metabolize host-derived apoplastic carbohydrates dependent on the sigma factor RpoS. The rpoS gene is an important strain factor for endophytic colonization by S. enterica during plant disease. Our results suggest that rpoS plays a crucial role during in planta colonization, balancing nutrient metabolism and stress responses.

中文翻译：

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RpoS有助于植物病害期间人类肠道病原菌成功地机会定居

随着与食用新鲜农产品有关的食源性疾病的增加，了解人类细菌性肠病原体与植物之间的相互作用非常重要。先前已经确定，患病的植物可以为肠内病原体的机会性内生定殖创造一个宽松的环境。然而，在植物病害中促成肠道病原体定殖的因素在很大程度上是未知的。在这里，我们显示了与植物病原体丁香假单胞菌pv一起接种时，菌株和植物宿主因子均显着增加了肠道病原体的数量。番茄。两种沙门氏菌菌株DM10000和14028S的代谢能力取决于σ因子RpoS，其代谢宿主衍生的质外性碳水化合物的能力不同。所述的rpoS基因是内生殖的重要因素应变肠道沙门氏菌植物病害中。我们的结果表明，rpoS在植物定植过程中起着至关重要的作用，平衡营养代谢和胁迫反应。