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Atypical thymoma in a horse: Diagnostic approach and application of an alternative histological classification system
Equine Veterinary Education ( IF 0.9 ) Pub Date : 2020-11-26 , DOI: 10.1111/eve.13419
T. Pudert 1 , A. Weyrich 2 , F. Geburek 3 , C. Herden 2 , M. Röcken 1
Affiliation  

Thymoma is a rare condition in horses. This case of a 24-year-old Warmblood gelding that was presented with oedema and signs of vascular congestion of the left forelimb caused by a thoracic mass is described. The diagnostic work-up included blood chemistry, cytology of pleural effusion, ultrasonography, radiography and the visualisation and collection of a tissue sample by thoracoscopy. Finally, post-mortem findings and histopathology revealed thymic epithelial neoplasia with histomorphologic features previously unreported in horses. The unique mixture of spindle-shaped and epithelioid tumour cells in combination with clear features of malignancy suggested the application of the Moran and Suster histological classification system for thymomas in humans (Moran and Suster, 2008, Curr. Treat. Options Oncol., 9, 288), which has not been reported in an equine case before and fits well to the present case.

中文翻译:

马的非典型胸腺瘤:替代组织学分类系统的诊断方法和应用

胸腺瘤是马的一种罕见疾病。该案例描述了 24 岁的温血马骟出现水肿和由胸部肿块引起的左前肢血管充血的迹象。诊断检查包括血液化学、胸腔积液细胞学、超声检查、放射线照相术以及通过胸腔镜检查组织样本的可视化和收集。最后,尸检结果和组织病理学揭示了胸腺上皮瘤变,其组织形态学特征以前未在马身上报告过。纺锤形和上皮样肿瘤细胞的独特混合物与明确的恶性肿瘤特征相结合,表明应将 Moran 和 Suster 组织学分类系统应用于人类胸腺瘤(Moran 和 Suster,2008 年,Curr. Treat. Options Oncol., 9, 288),之前没有在马病例中报道过,并且非常适合本病例。
更新日期:2020-11-26
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