This report describes gastric squamous cell carcinoma (GSCC) in seven horses. It records the clinical signs, treatment and outcomes. Main clinical signs were mostly nonspecific and included weight loss, anorexia, fever, tachycardia and tachypnoea. Some more suggestive clinical signs were observed such as recurrent choke, halitosis and hypersalivation. Chronic anaemia and hypoalbuminaemia were common findings. Gastroscopy identified a gastric mass in four cases (57.1%); however, visualisation of the stomach was precluded in the other three horses due to distal oesophageal neoplastic infiltration and compression. Gastric wall thickening was noticed using abdominal ultrasonography in four horses (57.1%). Neoplastic cells could only be detected in the peritoneal fluid of 2 out of 7 horses. Endoscopic-guided or transabdominal ultrasound-guided biopsies allowed an ante-mortem diagnosis in three horses (42.8%). Gastric masses were identified at post-mortem examination and metastasis were confirmed in the liver and/or the spleen for 4/4 cases. In the cases for which palliative therapy was attempted, most of the horses were subjected to euthanasia within 4 weeks. In conclusion, GSCC is an uncommon neoplastic disease in horses. A combination of diagnostic tests is often necessary to achieve a diagnosis, which is frequently only made late in the course of the disease. As a result, GSCC is commonly associated with a poor short-term prognosis.

中文翻译：

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马胃鳞状细胞癌：七例（2009-2019）

这份报告描述了七匹马的胃鳞状细胞癌 (GSCC)。它记录临床症状、治疗和结果。主要临床症状大多是非特异性的，包括体重减轻、厌食、发热、心动过速和呼吸急促。观察到一些更具提示性的临床症状，例如反复窒息、口臭和唾液分泌过多。慢性贫血和低白蛋白血症是常见的表现。胃镜检查发现 4 例（57.1%）有胃肿块；然而，由于远端食管肿瘤浸润和压迫，在其他三匹马中无法看到胃。在四匹马 (57.1%) 中使用腹部超声检查发现胃壁增厚。在 7 匹马中有 2 匹的腹腔液中只能检测到肿瘤细胞。内窥镜引导或经腹超声引导活检允许对三匹马（42.8%）进行死前诊断。在尸检中发现了胃肿块，4/4 例在肝脏和/或脾脏中证实了转移。在尝试姑息治疗的情况下，大多数马在 4 周内接受了安乐死。总之，GSCC 是一种罕见的马肿瘤性疾病。诊断测试的组合通常是实现诊断所必需的，而诊断通常仅在疾病过程的后期进行。因此，GSCC 通常与短期预后不良有关。在尝试姑息治疗的情况下，大多数马在 4 周内接受了安乐死。总之，GSCC 是一种罕见的马肿瘤性疾病。诊断测试的组合通常是实现诊断所必需的，而诊断通常仅在疾病过程的后期进行。因此，GSCC 通常与短期预后不良有关。在尝试姑息治疗的情况下，大多数马在 4 周内接受了安乐死。总之，GSCC 是一种罕见的马肿瘤性疾病。诊断测试的组合通常是实现诊断所必需的，而诊断通常仅在疾病过程的后期进行。因此，GSCC 通常与短期预后不良有关。