当前位置: X-MOL 学术NeuroImage › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Response modality-dependent categorical choice representations for vibrotactile comparisons
NeuroImage ( IF 5.7 ) Pub Date : 2021-02-01 , DOI: 10.1016/j.neuroimage.2020.117592
Yuan-hao Wu , Lisa A. Velenosi , Felix Blankenburg

Previous electrophysiological studies in monkeys and humans suggest that premotor regions are the primary loci for the encoding of perceptual choices during vibrotactile comparisons. However, these studies employed paradigms wherein choices were inextricably linked with the stimulus order and selection of manual movements. It remains largely unknown how vibrotactile choices are represented when they are decoupled from these sensorimotor components of the task. To address this question, we used fMRI-MVPA and a variant of the vibrotactile frequency discrimination task which enabled the isolation of choice-related signals from those related to stimulus order and selection of the manual decision reports. We identified the left contralateral dorsal premotor cortex (PMd) and intraparietal sulcus (IPS) as carrying information about vibrotactile choices. Our finding provides empirical evidence for an involvement of the PMd and IPS in vibrotactile decisions that goes above and beyond the coding of stimulus order and specific action selection. Considering findings from recent studies in animals, we speculate that the premotor region likely serves as a temporary storage site for information necessary for the specification of concrete manual movements, while the IPS might be more directly involved in the computation of choice. Moreover, this finding replicates results from our previous work using an oculomotor variant of the task, with the important difference that the informative premotor cluster identified in the previous work was centered in the bilateral frontal eye fields rather than in the PMd. Evidence from these two studies indicates that categorical choices in human vibrotactile comparisons are represented in a response modality-dependent manner.

中文翻译:

用于振动触觉比较的响应模式相关的分类选择表示

先前对猴子和人类的电生理学研究表明,在振动触觉比较过程中,运动前区是感知选择编码的主要位点。然而,这些研究采用了范式,其中选择与刺激顺序和手动动作的选择密不可分。当振动触觉选择与任务的这些感觉运动组件分离时,它们如何表示仍然是未知的。为了解决这个问题,我们使用了 fMRI-MVPA 和振动触觉频率鉴别任务的一个变体,它能够将选择相关的信号与刺激顺序和手动决策报告的选择相关的信号隔离开来。我们确定左侧对侧背侧运动前皮层 (PMd) 和顶内沟 (IPS) 携带有关振动触觉选择的信息。我们的发现为 PMd 和 IPS 参与超出刺激顺序编码和特定动作选择的振动触觉决策提供了经验证据。考虑到最近动物研究的结果,我们推测运动前区可能作为具体手动运动规范所需信息的临时存储场所,而 IPS 可能更直接地参与选择的计算。此外,这一发现复制了我们之前使用该任务的动眼神经变体的工作结果,重要的区别在于之前工作中确定的信息丰富的前运动集群集中在双侧额眼区而不是 PMd。
更新日期:2021-02-01
down
wechat
bug