The design strategy and the performance of binaphthyl-based chiral ligands were evaluated with computation and enantioselective addition of diethylzinc to aromatic aldehydes. Under optimized conditions, enantioselective addition of diethylzinc to aromatic aldehydes provided the desired optically active secondary alcohols in high isolated yields (up to 91%) and excellent enantiomeric excesses (up to 98% ee).

中文翻译：

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联萘基手性配体：设计、合成和评价其在二乙基锌对映选择性加成芳香醛中的性能

通过计算和二乙基锌与芳香醛的对映选择性加成，评估了联萘基手性配体的设计策略和性能。在优化条件下，将二乙基锌选择性地添加到芳香醛中，以高分离产率（高达 91%）和出色的对映体过量（高达 98% ee）提供了所需的光学活性仲醇。